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Halofuginone - CAS# 55837-20-2 ephalosporin C sodium InChiKey: WIJZXSAJMHAVGX-DHLKQENFSA-N

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Description

InChiKey: WIJZXSAJMHAVGX-DHLKQENFSA-N

In a kinase selectivity assessment against a panel of 250 protein kinases at 3 μM

PubMed Central PMCID: PMC4101245

Chemical Name:    3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone

and mRNA expression of the NF-κB-driven chemokine genes CCL20 and KC

Halofuginone - CAS# 55837-20-2 ephalosporin C sodium InChiKey: WIJZXSAJMHAVGX-DHLKQENFSA-NHalofuginone, CAS No. 55837 20 2, also known as RU 19110, is a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP 2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. These

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